October 16–20, 2015
Marco Island Marriott Beach Resort, Golf Club & Spa
Marco Island, Florida
Program Detail
Friday Oct 16, 2015
Session I
Chair: Michael Graner
Michael Graner, University of Colorado
Opening of ASEMV2015
Lawrence Rajendran
Beckman/Coulter Lecture: Role of membrane trafficking in Alzheimer’s disease
Johan Skog, Exosome Diagnostics
Exosome-based clinical testing: application to prostate cancer
Opening reception
Saturday Oct 17, 2015
Session II
Co-Chairs: Xandra Breakefield & Johan Skog
Louise Laurent, UC San Diego
Discovery of extracellular miRNA biomarkers for placental dysfunction
Florin Selaru, Johns Hopkins University
Treatment of desmoplastic cancers with extracellular vesicles
Alissa Weaver, Vanderbilt University
KRAS signaling regulates Argonaute 2 (Ago2) and miRNA sorting into exosomes
Fatah Kashanchi, George Mason University
Exosome from latent virally infected cells including HIV, HTLV-1, RVFV, and Ebola control innate immune response in recipient cells
Ritankar Majumdar, NCI/NIH
Exosomes Mediate LTB4 Release During Neutrophil Chemotaxis
Tomas Szul, University of Alabama Birmingham
Toll-Like Receptor 4 Engagement Mediates Prolyl Endopeptidase Release from Airway Epithelia via Exosomes
Harmeet Malhi, Mayo Clinic
IRE1alpha mediates the release of ceramide enriched extracellular vesicles from hepatocytes which activate macrophages
Masamitsu Kanada, Stanford University
Extracellular vesicle-mediated delivery of prodrug-converting enzymes for cancer therapy
Maria Mirotsou, Capricor Therapeutics
Development of cardiosphere-derived cell extracellular vesicles for regenerative medicine
Travis Antes, SystemsBiosciences
Engineering Therapeutic Nanoshuttles
Session III
Chair: Lawrence Rajendran
Stefan Momma, University Hospital Frankfurt
Caris Discovery Lecture: Tracing extracellular vesicle-mediated transfer of functional RNA in vivo
Dolores Di Vizio, Cedars Sinai
Tumor-derived large oncosomes contain kinase activity and can modulate transcription factor activation in the tumor environment
Exosome Stories (Various Speakers)
Evening Poster Session A/Reception
Sunday Oct 18, 2015
Session IV
Co-Chairs: Alissa Weaver and Fatah Kashanchi
Xandra Breakefield, MGH/Harvard
Extracellular RNA in brain tumors – saboteurs and biomarkers
Clark Chen, UC San Diego
CSF exosomal miRNAs as a biomarker platform for glioblastoma
John Semmes
Targeting extracellular vesicles for biomarker discovery and as potential assay vehicles
Muller Fabri, University of Southern California
Exosomic microRNA exchange promotes drug resistance
Y. Peng Loh, NICHD/NIH
Carboxypeptidase E: A prognostic cancer biomarker in tumors and circulating exosomes
Goran Ronquist
Proteomic Profiling of Detergent Resistant Membranes (Lipid Rafts) of Prostasomes
Andrew Hoffman, Tufts University
Are exosomes the next nanotheranostic frontier for cardiac disease? Explorations in a canine spontaneous mitral valve disease model
Sasha Vlassov, Life Technologies
Exosomes as source of biomarkers
Huiping Liu, Case Western Reserve University
Developing exosome-based therapeutics targeting cancer stem cells
A. C. Matin, Stanford University
Use of a new visualizable prodrug regimen for specific targeting of Her2 positive breast cancer using exosomes
Session V
Chair: Stephen Gould
Geoffrey de Couto, Cedars Sinai Heart Institute
Biodistribution of cardiosphere-derived cell exosomes: preferential uptake and polarization by macrophages after systemic delivery
Norman Haughey, Johns Hopkins University
Exosystems regulate communication between the brain and immune system via the liver
L. Shannon Holliday
Extracellular vesicles released by osteoclasts inhibit osteoclastogenesis in 1,25- dihydroxyvitamin D3-stimulated mouse marrow cultures
Evening Poster Session B/Reception
Monday Oct 19, 2015
Session VI
Chair: Stephen Gould
Michael Graner, University of Colorado
Transcriptional regulator proteins in EVs: the potential to mediate downstream pathways
Jeff Franklin, Vanderbilt University
Oncogene patterning of the tumor microenvironment via exosomes
Mikhail Skliar, University of Utah
Size and shape characterization of serum extracellular vesicles in hydrated and dessicated forms
Antonio De Maio, UC San Diego
Heat shock increases the production of extracellular vesicles
Janos Zempleni, University of Nebraska
The intestinal transport of bovine milk exosomes is mediated by endocytosis in human colon carcinoma Caco-2 cells and rat small intestinal IEC-6 cells
Martin Schlumpberger, Qiagen
Rapid Isolation of Intact Exosomes and Extracellular Vesicles
Kirsi Rilla, University of Eastern Finland
Correlative light and electron microscopy is a powerful method to study interactions of extracellular vesicles with recipient cells
Erez Eitan, NIA/NIH
Lysosome status modulates exosome functions in intercellular signaling and intracellular protein disposal
Sarah Fernando, University of British Columbia
Extracellular vesicles from amyotrophic lateral sclerosis tissues have misfolded SOD1 cargo and are implicated in propagation of protein misfolding